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Human Protein Atlas
hpa secretome dataset Hpa Secretome Dataset, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/secretome+dataset/pm41309504-412-20-17?v=Human+Protein+Atlas Average 86 stars, based on 1 article reviews
hpa secretome dataset - by Bioz Stars,
2026-07
86/100 stars
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Buy from Supplier |
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Human Protein Atlas
hpa secretome datasets across diverse tissues ![]() Hpa Secretome Datasets Across Diverse Tissues, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/secretome+dataset/bio_rxiv__2025__09__23__677404-430-17-14?v=Human+Protein+Atlas Average 86 stars, based on 1 article reviews
hpa secretome datasets across diverse tissues - by Bioz Stars,
2026-07
86/100 stars
|
Buy from Supplier |
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Journal: bioRxiv
Article Title: A Rare Multipotent Peg-like Epithelial Cell is a Candidate Cell-of-Origin for High-Grade Serous Ovarian Cancer
doi: 10.1101/2025.09.23.677404
Figure Lengend Snippet: (A) Overview of proteomic and secretome datasets generated from biobank specimens and utilized from public sources. (B) Experimental workflow for identifying secreted molecules across the FT epithelium and their subclusters. (C and D) Venn diagrams comparing protein overlap between datasets: tissue secretome vs. public FT lavage secretome ( C ), and tissue secretome vs. EpCAM⁺ Lin - cell proteome ( D ). (E) Venn diagram showing overlap between the inferred EpCAM⁺ Lin - cell secretome (shared proteins from tissue secretome and EpCAM⁺ proteome) and the secretome of 2D-cultured cells. (F) UMAP of the integrated epithelial subset showing expression of a signature derived from all genes encoding proteins found in the EpCAM⁺ cell proteome. (G) UMAP displaying expression of a refined signature representing overlapping genes from the tissue secretome and EpCAM⁺ cell proteome. (H) Bar plot quantifying the number of secreted molecules from the tissue secretome detected across epithelial subclusters. (I) Electron microscopy (EM) image of an FT organoid showing secretory granules along the apical surface of multiciliated and secretory cells. Annotations: C = cilia; MV = microvilli; S = secretory granules. Scale bar, 10 µm. (J) Table listing the top 20 differentially expressed secretory molecules from each epithelial subcluster. Color shading reflects the presence of each gene’s protein product in the proteome and/or secretome datasets shown in panel B , indicating relative support across modalities. See Supplementary Figure 6 for additional related data .
Article Snippet: A comprehensive reference list of human secreted proteins was compiled from multiple sources: (1)
Techniques: Generated, Cell Culture, Expressing, Derivative Assay, Electron Microscopy